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  • 17
    Paper name
    Neutrophil-derived itaconate facilitates tiered pulmonary inflammation via Kdm5b-associated epigenetic remodeling in alveolar macrophages.
    Author
    Lim G*, Kim J*, Park D, Lee J, Roh YJ, Yang M, Lee S, Yang S, Baek S, Park J, Lim HC, Lee J, Kim S, Seo H, Kim Y, Jung SM, Yang H, Sun P, Lee SE, Kang YE, Park Y, Son YM, Yi H, Hong JY, Luis FM, Kang DH, Kim C#, Yoon S#, and Choi DW#
    Journal+date
    Cell Reports. 2026 Jun.
    Link
    https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00490-0

    Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), present a s...

  • 16
    Paper name
    Methionine metabolism is linked with phospholipid and glutamine metabolism to drive ferroptosis
    Author
    Kim JW*, Jang SY*, Roh YJ*, Ju Y, Kang JB, Park BS, Lee JY, Kim MW, Jeong BJ, Jung W, Oh KJ, Kim WK, Han BS, Bae KH, Kim T, Kang YP, Yoo HM, Kim C, Dixon SJ, Choi DW#, Hwang GS#, Lee EW#
    Journal, date
    Cell Reports. 2026 Mar
    Link
    https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00235-4

    Ferroptosis is a lipid peroxidation-induced cell death mechanism that is regulated by amino acid met...

  • 15
    Paper name
    Microbiota-derived metabolite, 3-phenyllactic acid, prolongs healthspan by enhancing mitochondrial function and stress resilience via SKN-1/ATFS-1.
    Author
    Kim J*, Jo Y*, Lim G, Ji Y, Roh J, Kim W, Yi H#, Choi DW#, Cho D#, and Ryu D#.
    Journal, date
    Nature Communications. 2024 Dec.
    Link
    https://www.nature.com/articles/s41467-024-55015-1

    The mechanisms underlying the impact of probiotic supplementation on health remain largely elusive....

  • 14
    Journal name
    Binge drinking triggers VGLUT3-mediated glutamate secretion and subsequent hepatic inflammation by activating mGluR5/NOX2 in Kupffer cells.
    Author
    Yang K, Kim K, Ryu T, Shim YR, Kim HH, Choi SE, Kim MJ, Chung KPS, Lee E, Lee KW, Jeon J, Kim P, Kim YS, Ku T, Jeong H, Nam KT, Lim G, Choi DW, Kim SH, Eun HS, Kim W, Jeong WI.
    Journal+Date
    Nature Communications. 2025 Jul.
    Link
    https://www.nature.com/articles/s41467-025-60820-3
  • 13
    Journal name
    Metabolic Sparks in the Liver: Metabolic and Epigenetic Reprogramming in Hepatic Stellate Cells Activation and Its Implications for Human Metabolic Diseases.
    Author
    Roh YJ*, Kim H*, Choi DW.
    Journal+Date
    Diabetes Metabolism Joural. 2025 May
    Link
    https://e-dmj.org/journal/view.php?doi=10.4093/dmj.2025.0195
  • 12
    Journal name
    Unraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses.
    Journal name
    Lee SE, Park S, Yi S, Choi NR, Lim MA, Chang JW, Won H, Kim JR, Ko HM, Chung E, Park YJ, Cho SW, Yu HW, Choi JY, Yeo M, Yi B, Yi K, Lim J, Koh J, Lee MJ, Heo JY, Yoon SJ, Kwon SW, Park J, Chu IS, Kim JM, Kim S, Shan Y, Liu L, Hong S, Choi DW, Park J, Ju YS, Shong M, Kim S, Koo BS and Kang YE.
    Journal+Date
    Nature Communications. 2024 Feb.
    Link
    https://www.nature.com/articles/s41467-024-45366-0
  • 11
    Journal name
    Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA.
    Author
    Ngo J*, Choi DW*, Chen J, Shimir A, Stanley IA, Lako A, Ficarro S, Chapuy B, Rodig S, Shipp MA, Marto JA, Danial NN and Shirihai O.
    Journal+Date
    EMBO Journal. 2023 Mar.
    Link
    https://link.springer.com/article/10.15252/embj.2022111901
  • 10
    Journal name
    The role of immunomodulatory metabolites in shaping the inflammatory response of macrophages.
    Author
    Park D*, Lim G*, Yoon SJ, Yi HS, and Choi DW.
    Journal+Date
    BMB Reports. 2022 Nov
    Link
    https://www.bmbreports.org/journal/view.html?volume=55&number=11&spage=519
  • 9
    Journal name
    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation.
    Author
    Yoo HJ*, Choi DW#, Roh YJ, Kim S, Lee HM, Lim G, Park D, Shin D, Lee HJ, Lee BC, Kim J#.
    Journal+Date
    Cell Reports. 2022 Nov
    Link
    https://www.sciencedirect.com/science/article/pii/S2211124722014632
  • 8
    Journal name
    MCL-1 is a Master Regulator of Cancer Dependency on Fatty Acid Oxidation.
    Author
    Prew M, Adhikary U, Choi DW, Paulo J, Budhraja A, Opferman J, Gygi S, Danial NN, and Walensky L.
    Journal+Date
    Cell Reports. 2022 Oct.
    Link
    https://www.sciencedirect.com/science/article/pii/S2211124722012864?via%3Dihub
  • 7
    Journal name
    Glucose dependent partitioning of arginine to the urea cycle protects b-cell from inflammation.
    Author
    Fu A, Alvarez-Perez JC, Avizonis D, Kin T, Ficarro S, Choi DW, Karakose E, Badur M, Evans L, Rosselot C, Bridon G , Bird G, Seo H, Dhe-Paganon S, Kamphorst J, Stewart A, Shapiro J, Marto JA, Walensky L, Jones R, Garcia-Ocana A, Danial NN.
    Journal+Date
    Nature Metabolism. 2020 May
    Link
    https://www.nature.com/articles/s42255-020-0199-4
  • 6
    Journal name
    HCF-1 regulates de novo lipogenesis through a nutrient sensitive complex with ChREBP.
    Author
    Lane EA*, Choi DW*, Garcia-Haro L, Levine ZG, Tedoldi M, Walker S and Danial NN.
    Journal+Date
    Molecular Cell. 2019 Jul
    Link
    https://www.sciencedirect.com/science/article/pii/S1097276519303910?via%3Dihub
  • 5
    Journal name
    The deubuiquitinating enzyme USP20 stabilize ULK1 and promotes autophagy initiation.
    Author
    Kim JH*, Seo D*, Kim SJ*, Choi DW*, Park JS, Ha J, Jung SM, Seo KW, Lee EW, Lee YS, Cheong H, Choi CY and Park SH.
    Journal+Date
    EMBO reports. 2018 Apr
    Link
    https://link.springer.com/article/10.15252/embr.201744378
  • 4
    Journal name
    Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets.
    Author
    Norberg E, Lako A, Chen P, Stanley IA, Zhou F, Ficarro S, Chapuy B, Chen L, Rodig S, Shin D, Choi DW, Lee S, Shipp MA, Marto JA and Danial NN.
    Journal+Date
    Cell Death and Differentiation. 2017 Feb
    Link
    https://www.nature.com/articles/cdd2016116
  • 3
    Journal name
    HIPK2 tumor suppressor regulates tumor cell growth via the phosphorylation of Notch1.
    Author
    Ann E, Kim M, Yoon J, Ahn J, Jo E, Lee H, Lee H, Kang H, Choi DW, Chun K, Lee JS, Choi CY, Ferrando A, and Park H.
    Journal+Date
    Cancer Research. 2016 Aug.
    Link
    https://aacrjournals.org/cancerres/article/76/16/4728/544281/Tumor-Suppressor-HIPK2-Regulates-Malignant-Growth?guestAccessKey=